|
KMID : 0358419740170080479
|
|
Korean Journal of Obstetrics and Gynecology
1974 Volume.17 No. 8 p.479 ~ p.484
|
|
|
Electrophoretic Study of Protein in the Cerebrospinal Fluid of Eclampsia
|
|
노대식/Ro DS
송상환/Song SW
|
|
|
Abstract
|
|
|
|
Eclampsia is one of the most serious complications and has been studied for a long time in order to clarify its etiology, pathophysiology or treatment. However, as of yet the cause of eclampsia is not clear, and a few studies on changes of cerebrospinal fluid have been carried out. Recently, Morrion et al. and Choi ot al. have found that protein content of cerebrospinal fluid is higher in eclampsia than in normal pregnancy. This study was carried out to know which protein fractions in cerebrospinal fluid are specificially elevated in eclampsia. Cellulose acetate electrophoresis was undertaken to evaluate the protein fractions in cerebrospinal fluid in 10 normal pregnant women, and 12 eclamptic cases. The results were as follows. 1) Beta and gamma globulins tended to be elevated in eclampsia. 2) Gamma globulin showed significant elevation more than beta globulin. 3) Elevation of both beta and gamma globulins cerebrospinal fluid was not related to those of serum. In summary, this results suggested that gamma globulin elevation of cerebrospinal fluid was a specific change due to eclamptic brain pathology and could be helpful to diagnose eclampsia from other convulsive disorders.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
  
|